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Invitrogen™ OTUB1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558684

Product Code. 15736561

  • 574.00€ / 100µL

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Description

Description

Immunogen sequence: AAEEPQQQKQ EPLGSDSEGV NCLAYDEAIM AQQDRIQQEI AVQNPLVSER LELSVLYKEY AEDDNIYQQK IKDLHKKYSY IRKTRPD Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

The product of this gene is a member of the OTU superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

OTUB1
Polyclonal
Unconjugated
OTUB1
AI850305; Deubiquitinating enzyme OTUB1; deubiquitinating enzyme OTUB1 {ECO:0000250; EMBL:AAI66771.1}; FLJ20113; FLJ40710; hOTU1; HSPC263; hypothetical protein LOC540984; MGC111158; MGC4584; OTB1; OTU deubiquitinase, ubiquitin aldehyde binding 1; OTU domain, ubiquitin aldehyde binding 1; OTU domain-containing ubiquitin aldehyde-binding protein 1; OTU domain-containing ubiquitin aldehyde-binding protein 1 {ECO:0000250; OTU1; OTUB1; otub1 {ECO:0000312; otubain 1; otubain-1; otubain-1 {ECO:0000250; OTU-domain Ubal-binding 1; Ubiquitin thioesterase OTUB1; ubiquitin thioesterase OTUB1 {ECO:0000250; ubiquitin-specific protease otubain 1; ubiquitin-specific-processing protease OTUB1; ubiquitin-specific-processing protease OTUB1 {ECO:0000250; UniProtKB:Q7TQI3}
Rabbit
Antigen affinity chromatography
RUO
107260, 293705, 55611
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
B2RYG6, Q7TQI3, Q96FW1
OTUB1
Recombinant protein corresponding to Human OTUB1. Recombinant protein control fragment (Product #RP-95850).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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