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  7. N,O-Dimethylhydroxylamine hydrochloride, 98%, Thermo Scientific Chemicals

N,O-Dimethylhydroxylamine hydrochloride, 98%, Thermo Scientific Chemicals

Product Code. 11488067
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Quantity:
5 g
25 g
100 g

Description

N,O-Dimethylhydroxylamine hydrochloride is used as a reagent in the preparation of 2-acyloxazoles from 2-oxazolemagnesium chloride and N-methoxy-N-methyl-3-oxo-butyramide from diketene. It is also used in amide coupling reactions to form Weinreb amides, which are useful in the Weinreb ketone synthesis. In addition, it is used in the preparation of an inhibitor of the NLS-derived BC peptides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,O-Dimethylhydroxylamine hydrochloride is used as a reagent in the preparation of 2-acyloxazoles from 2-oxazolemagnesium chloride and N-methoxy-N-methyl-3-oxo-butyramide from diketene. It is also used in amide coupling reactions to form Weinreb amides, which are useful in the Weinreb ketone synthesis. In addition, it is used in the preparation of an inhibitor of the NLS-derived BC peptides.

Solubility
Soluble in water, dimethyl sulfoxide and methanol.

Notes
Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 6638-79-5
Molecular Formula C2H8ClNO
Molecular Weight (g/mol) 97.54
MDL Number MFCD00012485
InChI Key USZLCYNVCCDPLQ-UHFFFAOYSA-N
Synonym n,o-dimethylhydroxylamine hydrochloride, n,o-dimethylhydroxylamine hcl, n-methoxymethylamine hydrochloride, methanamine, n-methoxy-, hydrochloride, o,n-dimethylhydroxylamine hydrochloride, n-methoxymethanamine hydrochloride, o,n-dimethyl-hydroxylamine hydrochloride, methoxy methyl amine hydrochloride, n,o-dimethylhydroxyamine hydrochloride, n,o-dimethylhydroxylaminehydrochloride
PubChem CID 81138
SMILES [H+].[Cl-].CNOC

Specifications

Melting Point 112°C to 115°C
Quantity 100 g
Beilstein 3650353
Sensitivity Hygroscopic
Solubility Information Soluble in water,dimethyl sulfoxide and methanol.
IUPAC Name N-methoxymethanamine;hydrochloride
Formula Weight 97.55
Percent Purity 98%
Chemical Name or Material N,O-Dimethylhydroxylamine hydrochloride

Safety and Handling

compliance-icons
Product Identifier
  • N,O-Dimethylhydroxylamine hydrochloride
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : N,O-Dimethylhydroxylamine hydrochloride

RUO – Research Use Only

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