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  7. N-Ethylmaleimide, 98+%, Thermo Scientific Chemicals

N-Ethylmaleimide, 98+%, Thermo Scientific Chemicals

Product Code. 11330014
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Quantity:
10 g
50 g
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.

Solubility
Soluble in ethanol, water, chloroform, methanol and toluene.

Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, strong acids and strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 128-53-0
Molecular Formula C6H7NO2
Molecular Weight (g/mol) 125.127
MDL Number MFCD00005509
InChI Key HDFGOPSGAURCEO-UHFFFAOYSA-N
Synonym n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide
PubChem CID 4362
ChEBI CHEBI:44485
IUPAC Name 1-ethylpyrrole-2,5-dione
SMILES CCN1C(=O)C=CC1=O

Specifications

Melting Point 43°C to 46°C
Boiling Point 209°C to 211°C
Flash Point 73°C (163°F)
Odor Pungent
Quantity 10 g
UN Number UN2928
Beilstein 112448
Sensitivity Light sensitive
Merck Index 14,3822
Solubility Information Soluble in ethanol,water,chloroform,methanol and toluene.
Formula Weight 125.13
Percent Purity ≥98%
Chemical Name or Material N-Ethylmaleimide
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Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • N-Ethylmaleimide
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 2
  • Skin corrosion/irritation Category 1 B
  • Acute toxicity Category 4
  • Skin sensitiser Category 1
 Hazard Statement
  • H300-Fatal if swallowed.
  • H312-Harmful in contact with skin.
  • H314-Causes severe skin burns and eye damage.
  • H317-May cause an allergic skin reaction.
 Precautionary Statement
  • P260-Do not breathe dust/fume/gas/mist/vapours/spray.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

RUO – Research Use Only

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