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Tocris Bioscience™ (±)-ML 209

RORγt inverse agonist; suppresses Th17 cell differentiation

Brand: Tocris Bioscience™ 5987/10

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Product Code. 18791068

188.00€ / 10mg

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Description

(±)-ML 209 is a RORγt inverse agonist (IC50 = 460 nM). Suppresses Th17 cell differentiation and IL17A expression in vitro. Does not suppress transcription of RORα. Minimal activity displayed on ERα, LXRα and thyroid hormone receptors (IC50 values >4.4 μM).

Specifications

Color	White
Target Proteins	Nuclear Receptor Antagonists
Molecular Formula	C₂₅H₃₁NO₆
Solubility	Soluble to 100mM in DMSO
For Use With (Application)	Inverse agonism Th17 cell differentiation, inhibits MS multiple sclerosis

Product Type	Inhibitor
CAS	1334526-14-5
Formula Weight	441g/mol
Content And Storage	Store at -20°C
Quantity	10 mg

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Tocris Bioscience™ (±)-ML 209

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