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  8. Mirin, Tocris Bioscience™

Mirin, Tocris Bioscience™

Product Code. 18036022
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

MRN-ATM pathway inhibitor

Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor that blocks the 3' and 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC50 = 12 μM) and induces G2 cell cycle arrest. Also blocks homology-directed repair in vitro.

Chemical Identifiers

CAS 1198097-97-0
Molecular Formula C10H8N2O2S
Molecular Weight (g/mol) 220.246
InChI Key YBHQCJILTOVLHD-YVMONPNESA-N
Synonym mirin, z-5-4-hydroxybenzylidene-2-imino-1,3-thiazolidin-4-one, mrn-atm pathway inhibitor, mirin, 5z-5-4-hydroxyphenyl methylidene-2-imino-1,3-thiazolidin-4-one, 5-4-hydroxybenzylidene-2-iminothiazolidin-4-one, mrn-atm pathway inhibitor,mirin, mirin hplc , powder, 2-amino-5-4-hydroxyphenyl methylene-4 5h-thiazolone, 5z-5-4-hydroxybenzylidene-2-imino-1,3-thiazolidin-4-one, 5z-2-amino-5-4-hydroxyphenyl methylidene-1,3-thiazol-4-one
PubChem CID 1206243
IUPAC Name (5Z)-2-amino-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazol-4-one
SMILES C1=CC(=CC=C1C=C2C(=O)N=C(S2)N)O

Specifications

Quantity 10 mg
Formula Weight 220.25
Percent Purity >99%
Chemical Name or Material Mirin
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