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![Invitrogen Human MET (cMET) [Y1235D], GST Tag Recombinant Protein Quantity:](https://assets.fishersci.com/TFS-Assets/LSG/product-images/Cell_Bio_Rec_Prot_Invitrogen_Vial.jpg-650.jpg)
Invitrogen™ Human MET (cMET) [Y1235D], GST Tag Recombinant Protein
Human MET (cMET) [Y1235D], GST Tag Recombinant Protein
Brand: Invitrogen™ A33559
This item is not returnable.
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Description
MET receptor tyrosine kinase is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kDa (alpha) and 145 kDa (beta). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue. Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion. MET (Y1235D) is one of the native mutant forms of MET.- Validated for use with the Z’-LYTE™ assay
- Available in multiple pack sizes for convenient use
Specifications
| NP_000236.2 | |
| 75.4 kDa | |
| METs (HGFRs) | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Recombinant, Active, Cytoplasmic, Mutant |
| Kinase Assay | |
| 100 μg | |
| aa 956 - 1390 | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol | |
| Insect | |
| Liquid |