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GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3).
Brand: GeneBLAzer™ K1716
Additional Details : Weight : 0.01000kg
Description
- Gene Symbol: M3
- Accession Number: NM_000740.2
- Population Status: Single Cell Clone Origin
- GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. no. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
- The GeneBLAzer™ M3-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50concentrations of Carbachol. In addition, GeneBLAzer™ M3-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
- The M3 receptor is localized in smooth muscle, exocrine glands, and the central nervous system. M3 has been implicated in autoimmune and neurological disorders.
Specifications
| Liquid Nitrogen | |
| GPCRs | |
| 2 x 106 Cells |
| Fluorescent | |
| M3-NFAT-bla CHO-K1 cells, M3-NFAT-bla CHO-K1 Assay Protocol, Certificate of Analysis | |
| Dividing Cells |