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Latrunculin B, Tocris Bioscience™

Product Code. 30000885
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Inhibitor of actin polymerization

Inhibitor of actin polymerization. Interacts with G-actin in a 1:1 ratio to inhibit polymerization into F-actin in vitro (IC50 values are ∽60 and ∽900 nM in absence and presence of calf serum, respectively). Marine toxin.

Specifications

CAS 76343-94-7
Molecular Formula C20H29NO5S
Linear Formula C20H29NO5S
MDL Number MFCD00270879
Quantity 1 mg
Synonym latrunculin b, lat-b, unii-lw7u308u7u, latrunculin b, latrunculia magnifica, 4r-4-1r,4s,5z,9z,13r,15r-15-hydroxy-4,9-dimethyl-11-oxo-12,16-dioxabicyclo 11.3.1 heptadeca-5,9-dien-15-yl-1,3-thiazolidin-2-one, lat b, +-latrunculin b, d07ehb, latrunculin b from latruncula magnifica, 2-thiazolidinone, 4-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo 11.3.1 heptadeca-4,8-dien-15-yl-, 1r*,4z,8z,10s*,13r*,15r* r*-+
Solubility Information Soluble to 50mM in DMSO and to 50mM in ethanol
InChI Key NSHPHXHGRHSMIK-JRIKCGFMSA-N
SMILES C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]2CSC(=O)N2)OC(=O)\C=C(C)/CC\C=C/1
IUPAC Name (4R)-4-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-1,3-thiazolidin-2-one
Molecular Weight (g/mol) 395.51
PubChem CID 6436219
ChEBI CHEBI:49703
Formula Weight 395.51
Percent Purity 0.95
Physical Form Lyophilized Film
Chemical Name or Material (4R)-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-d
Grade >97%
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