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Latrunculin B, Tocris Bioscience™
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Quantity:
1 mg
Description
Inhibitor of actin polymerization. Interacts with G-actin in a 1:1 ratio to inhibit polymerization into F-actin in vitro (IC50 values are ∽60 and ∽900 nM in absence and presence of calf serum, respectively). Marine toxin.
Specifications
Specifications
CAS | 76343-94-7 |
Molecular Formula | C20H29NO5S |
Linear Formula | C20H29NO5S |
MDL Number | MFCD00270879 |
Quantity | 1 mg |
Synonym | latrunculin b, lat-b, unii-lw7u308u7u, latrunculin b, latrunculia magnifica, 4r-4-1r,4s,5z,9z,13r,15r-15-hydroxy-4,9-dimethyl-11-oxo-12,16-dioxabicyclo 11.3.1 heptadeca-5,9-dien-15-yl-1,3-thiazolidin-2-one, lat b, +-latrunculin b, d07ehb, latrunculin b from latruncula magnifica, 2-thiazolidinone, 4-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo 11.3.1 heptadeca-4,8-dien-15-yl-, 1r*,4z,8z,10s*,13r*,15r* r*-+ |
Solubility Information | Soluble to 50mM in DMSO and to 50mM in ethanol |
InChI Key | NSHPHXHGRHSMIK-JRIKCGFMSA-N |
SMILES | C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]2CSC(=O)N2)OC(=O)\C=C(C)/CC\C=C/1 |
IUPAC Name | (4R)-4-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-1,3-thiazolidin-2-one |
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