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Kenpaullone, Tocris Bioscience™

Product Code. 18005952
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Quantity:
10 mg
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This item is not returnable. View return policy

Description

GSK-3β inhibitor; also inhibits cdks

GSK-3beta inhibitor (IC50 = 0.23 μM). Also inhibits cyclin dependent kinases (cdks) in the sub micromolar range (reported IC50 values are 0.4, 0.68-7 and 0.85 μM for cdk1, cdk2 and cdk5, respectively). Generates induced pluripotent stem cells (iPSCs) from somatic cells when used in combination with reprogramming factors; can replace Klf4.

Specifications

CAS 142273-20-9
Molecular Formula C16H11BrN2O
Quantity 10 mg
Synonym kenpaullone, 9-bromopaullone, 9-bromo-7,12-dihydroindolo 3,2-d 1 benzazepin-6 5h-one, indolo 3,2-d 1 benzazepin-6 5h-one,9-bromo-7,12-dihydro, 9-bromo-7,12-dihydro-indolo 3,2-d 1 benzazepin-6 5h-one, 9-bromo-7,12-dihydro-5h-indolo 3,2-d 1 benzazepin-6-one, 9-bromo-7,12-dihydro-indolo-3,2-d-1 benzazepin-6 5h-one, 9-bromo-7,12-dihydrobenzo 2,3 azepino 4,5-b indol-6 5h-one, indolo 3,2-d 1 benzazepin-6 5h-one, 9-bromo-7,12-dihydro
InChI Key QQUXFYAWXPMDOE-UHFFFAOYSA-N
SMILES C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br
IUPAC Name 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one
Molecular Weight (g/mol) 327.181
PubChem CID 3820
Formula Weight 327.18
Percent Purity >98%
Chemical Name or Material Kenpaullone
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