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  8. KC7F2, Tocris Bioscience™

KC7F2, Tocris Bioscience™

Product Code. 30001506
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

HIF-1α inhibitor; down-regulates HIF-1α protein synthesis

Inhibitor of HIF-1α. Thought to act via down-regulation of HIF-1α protein synthesis; reduces phosphorylation of eIF4E binding protein 1 (4EBP1) and p70 S6K in hypoxic conditions. Also blocks hypoxia-induced HIF-1α accumulation in a range of human cancer cell lines. Inhibits the expression of HIF target genes, such as carbonic anhydrase IX and MMP2.

Chemical Identifiers

CAS 927822-86-4
Molecular Formula C16H16Cl4N2O4S4
Molecular Weight (g/mol) 570.354
InChI Key REQLACDIZMLXIC-UHFFFAOYSA-N
Synonym kc7f2, unii-94c2dmm81l, n,n'-dithiodi-2,1-ethanediyl bis 2,5-dichlorobenzenesulfonamide, kc7f hplc, n,n'-dithiodi-2,1-ethanediyl bis 2,5-dichloro-benzenesulfonamide, o-2-aminoethyl-o'-2-carboxyethyl polyethylene glycol hydrochloride, n,n'-disulfanediylbis ethane-2,1-diyl bis 2,5-dichlorobenzenesulfonamide, 2,5-dichloro-n-2-2-2,5-dichlorobenzenesulfonamido ethyl disulfanyl ethyl benzenesulfonamide
PubChem CID 16047442
IUPAC Name 2,5-dichloro-N-[2-[2-[(2,5-dichlorophenyl)sulfonylamino]ethyldisulfanyl]ethyl]benzenesulfonamide
SMILES C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl

Specifications

Quantity 50 mg
Formula Weight 570.38
Percent Purity >98%
Chemical Name or Material KC7F2
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