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Ivermectin, Tocris Bioscience™

Product Code. 18752474
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Quantity:
100 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Allosteric modulator of α7 nicotinic receptors

Positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic and antiviral. Also modulates glutamate- and GABA-activated chloride channels. Potentiates glycine-gated currents at low concentrations (30 nM). Inhibits replication of SARS-CoV-2 in vitro (IC50 ∽ 2μM).

This product is composed of both Ivermectin B1a (>90%) and Ivermectin B1b.

Specifications

CAS 70288-86-7
Molecular Formula C48H74O14
Quantity 100 mg
Synonym ivermectin
InChI Key AZSNMRSAGSSBNP-RDKIRRGNSA-N
SMILES CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C
Molecular Weight (g/mol) 875.106
PubChem CID 122172888
Formula Weight 875.1
Percent Purity >96%
Chemical Name or Material Ivermectin
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