missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organonitrogen Compounds
  6. Arylhydroxamates
  7. Indirubin-3'-oxime, Tocris Bioscience™

Indirubin-3'-oxime, Tocris Bioscience™

Product Code. 18014482
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

GSK-3β inhibitor. Also inhibits other protein kinases

Inhibitor of GSK-3β (IC50 = 190 nM) and cyclin dependent kinases (cdks; IC50 values are 0.05, 0.18 and 0.25-0.5 βM for cdk9, cdk1 and cdk2, respectively). Also reported to inhibit AMPK, LCK and SGK. Inhibits cdk5- and GSK-3β-mediated tau phosphorylation. Induces cell cycle arrest and inhibits cell proliferation.

Chemical Identifiers

CAS 160807-49-8
Molecular Formula C16H11N3O2
Molecular Weight (g/mol) 277.28
MDL Number MFCD02683594
InChI Key LDEWQRSYYHTQRA-UHFFFAOYSA-N
Synonym indirubin-3'-monoxime, indirubin-3'-oxime, indirubin-3-oxime, indirubin-3monoxime, indirubin-3'-monooxime, indirubin-3-monoxime, 3-3-hydroxyamino-1h-indol-2-yl indol-2-one, indirubin-3′-monoxime, z-1h,1'h-2,3' biindolylidene-3,2'-dione-3-oxime, 3-1,3-dihydro-3-hydroxyimino-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
PubChem CID 5326739
IUPAC Name 3-(hydroxyamino)-1H,2'H-[2,3'-biindol]-2'-one
SMILES ONC1=C(NC2=CC=CC=C12)C1=C2C=CC=CC2=NC1=O

Specifications

Quantity 10 mg
Formula Weight 277.28
Percent Purity >99%
Chemical Name or Material Indirubin-3'-oxime
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.