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  7. IEM 1925 dihydrobromide, Tocris Bioscience™

IEM 1925 dihydrobromide, Tocris Bioscience™

Product Code. 18075452
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Quantity:
10 mg
50 mg
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Description

Voltage- and use-dependent open-channel antagonist of AMPA receptors

IEM 1925 dihydrobromide is a voltage- and use-dependent open-channel antagonist of AMPA receptors. Selective between subtypes; blocks GluA2 subunit-lacking receptors more potently than GluA2-containing receptors (KD for GluA2-containing AMPAR is 210 times higher at -80 mV). More potent than IEM 1460 (Cat. No. 1636) and IEM 1754 due to a slower unblocking rate. Alleviates inflammatory pain in a rat model of peripheral inflammation.

Chemical Identifiers

CAS 258282-23-4
Molecular Formula C17H30Br2N2
Molecular Weight (g/mol) 422.249
InChI Key ZCYUSVRXEKAQSL-UHFFFAOYSA-N
Synonym iem 1925 dihydrobromide, n-1-phenylcyclohexyl-1,5-pentanediamine dihydrobromide
PubChem CID 44561101
IUPAC Name N'-(1-phenylcyclohexyl)pentane-1,5-diamine;dihydrobromide
SMILES C1CCC(CC1)(C2=CC=CC=C2)NCCCCCN.Br.Br

Specifications

Quantity 10 mg
Formula Weight 422.24
Percent Purity 95%
Chemical Name or Material IEM 1925 dihydrobromide
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