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Invitrogen™ Human TSG-6 ELISA Kit
Human TSG-6 quantitates human TSG-6 in serum, plasma, supernatant.
656.00€ - 2635.00€
Specifications
| Accession Number | Hyaluronate-binding protein; TNF alpha induced protein 6; TNF alpha-induced protein 6; TNFAIP6; Tnfip6; TNF-stimulated gene 6 protein; TSG6; TSG-6; tumor necrosis factor alpha induced protein 6; tumor necrosis factor alpha-induced protein 6; tumor necrosis factor alpha-inducible protein 6; tumor necrosis factor induced protein 6; tumor necrosis factor, alpha induced protein 6; tumor necrosis factor, alpha-induced protein 6; tumor necrosis factor-inducible gene 6 protein; tumor necrosis factor-stimulated gene-6 protein |
|---|---|
| Assay Range | 0.2 to 50 ng/mL |
| Assay Sensitivity | 0.2 ng/mL |
| Conjugate | Biotin |
| Product Type | ELISA |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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17165259
|
Invitrogen™
EH472RBX5 |
5 x 96 Tests |
2635.00€
Each |
Estimated Shipment: 30-12-2024
Log in to see stock. |
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|
17124783
|
Invitrogen™
EH472RB |
96 Tests |
656.00€
Pack of 96 |
Estimated Shipment: 02-01-2025
Log in to see stock. |
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Description
Human TSG-6 quantitates human TSG-6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human TSG-6.
The TSG6 gene is transcribed in normal fibroblasts and activated by binding of the cytokines TNF alpha and IL-1 at AP-1 and NF-IL6 sites in its promoter. TSG-6 is a glycoprotein and a member of the hyaluronan-binding protein family, which includes cartilage link protein, proteoglycan core protein and the adhesion receptor CD44. TSG-6 is highly homologous to CD44, particularly in the hyaluronic acid-binding domain. TSG-6 is found in TNF-treated cells; its expression is rapidly activated by TNF alpha, IL-1 and lipopolysaccharide in normal fibroblasts, peripheral blood mononuclear cells, synovial cells and chondrocytes. The presence of TSG-6 in synovial fluid suggests a possible role in rheumatoid arthritis. TSG-6 forms a stable complex with components of the serine protease inhibitor, inter-alpha-inhibitor (I alpha I)). TSG-6 potentiates the inhibitory effect of l alpha l on the protease activity of plasmin. Through their cooperative inhibitory effect on plasmin, TSG-6 and l alpha l can modulate the protease network and thus inhibit inflammation.Specifications
| Hyaluronate-binding protein; TNF alpha induced protein 6; TNF alpha-induced protein 6; TNFAIP6; Tnfip6; TNF-stimulated gene 6 protein; TSG6; TSG-6; tumor necrosis factor alpha induced protein 6; tumor necrosis factor alpha-induced protein 6; tumor necrosis factor alpha-inducible protein 6; tumor necrosis factor induced protein 6; tumor necrosis factor, alpha induced protein 6; tumor necrosis factor, alpha-induced protein 6; tumor necrosis factor-inducible gene 6 protein; tumor necrosis factor-stimulated gene-6 protein | |
| 0.2 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| TNFAIP6 | |
| <10% | |
| HRP | |
| Serum, 50 μL; Supernatant, 50 μL; Plasma, 50 μL | |
| TNFAIP6 | |
| 4 hr 45 min |
| 0.2 to 50 ng/mL | |
| Biotin | |
| Plasma, Serum, Supernatant | |
| P98066 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| Research Use Only | |
| 2°C to 8°C | |
| 1 hr 20 min |