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Gibco™ Human Oncostatin M (209 aa) Recombinant Protein, PeproTech®
E. coli Recombinant Protein
Brand: Gibco™ 300-10T-250UG
This item is not returnable.
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Description
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
Specifications
| P13725 | |
| protein with no preservative | |
| 23.6 | |
| 250 μg | |
| -20°C | |
| <1 EU/μg | |
| OSM | |
| Unconjugated | |
| AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRR | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 5008 | |
| Human Oncostatin M (209 aa) | |
| E. coli | |
| RUO | |
| MGC20461; OncoM; oncostatin M; oncostatin-M; OSM | |
| Human | |
| Recombinant | |
| Lyophilized |