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  7. GRI 977143, Tocris Bioscience™

GRI 977143, Tocris Bioscience™

Product Code. 30001547
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Quantity:
10 mg
50 mg
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Description

Selective LPA2 receptor non-lipid agonist

Selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.

Chemical Identifiers

CAS 325850-81-5
Molecular Formula C22H17NO4S
Molecular Weight (g/mol) 391.441
InChI Key GMVZUCHUOYUMLL-UHFFFAOYSA-N
Synonym unii-m3l07r4zep, m3l07r4zep, 2-3-1,3-dioxo-1h-benz de isoquinolin-2 3h-yl propyl thio benzoic acid, 2-3-1,3-dioxo-1h-benzo de isoquinolin-2 3h-yl propyl thio benzoic acid, 2-3-1,3-dioxo-1h benzo de isoquinolin-2 3h-yl propyl thio benzoic acid, 2-3-1,3-dioxo-1h-benzo de isoquinolin-2 3h-yl propyl sulfanyl benzoic acid, 2-3-2,4-dioxo-3-azatricyclo 7.3.1.0?, 1 3 trideca-1 13 ,5,7,9,11-pentaen-3-yl propyl sulfanyl benzoic acid, 2-3-1,3-dioxo-1h,3h-benzo de isoquinolin-2-yl-propylsulfanyl-benzoic acid
PubChem CID 3114900
IUPAC Name 2-[3-(1,3-dioxobenzo[de]isoquinolin-2-yl)propylsulfanyl]benzoic acid
SMILES C1=CC=C(C(=C1)C(=O)O)SCCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O

Specifications

Quantity 50 mg
Formula Weight 391.44
Percent Purity >98%
Chemical Name or Material GRI 977143
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