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GPBAR-A, Tocris Bioscience™

Product Code. 30001672
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Quantity:
10 mg
50 mg
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Description

GPBA receptor (TGR5) agonist

GPBA receptor agonist. Upregulates GLP-1 secretion from intestinal cultures. Increases MQAE-fluorescence suggesting a decrease in intracellular chloride concentration in gallbladder epithelial cells.

Chemical Identifiers

CAS 877052-79-4
Molecular Formula C23H15F7N2O2
Molecular Weight (g/mol) 484.374
InChI Key ZIXNJVGTAXRKAP-UHFFFAOYSA-N
Synonym gpbar-a, 4-3,5-bis trifluoromethyl phenyl methyl-6-2-fluorophenyl-4,5-dihydro-pyrido 3,2-f-1,4-oxazepin-3 2h-one, gpbar-a hplc, 4-3,5-bis trifluoromethyl phenyl methyl-6-2-fluorophenyl-2h,5h-pyrido 3,2-f 1,4 oxazepin-3-one
PubChem CID 11656002
IUPAC Name 4-[[3,5-bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-5H-pyrido[3,2-f][1,4]oxazepin-3-one
SMILES C1C2=C(C=CN=C2OCC(=O)N1CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C4=CC=CC=C4F

Specifications

Quantity 50 mg
Formula Weight 484.37
Percent Purity >98%
Chemical Name or Material GPBAR-A
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