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Thermo Scientific™ GeneBLAzer™ H2-CRE-bla HEK 293T Cells

GeneBLAzer™ H2-CRE-bla HEK293T cells contain the human Histamine Receptor 2 (H2) stably integrated into the CellSensor™ CRE-bla HEK293T cell line.

Brand: Thermo Scientific™ K1707

Product Code. 10165653

16470.00€ / Each

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Estimated Shipment: 02-04-2025
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Description

GeneBLAzer™ H2-CRE-bla HEK293T cells contain the human Histamine Receptor 2 (H2) stably integrated into the CellSensor™ CRE-bla HEK293T cell line. CellSensor™ CRE-bla HEK293T cells (Cat. No. K1540) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ H2-CRE-bla HEK293T cells are functionally validated for Z' and EC₅₀ concentrations of Histamine. In addition, GeneBLAzer™ H2-CRE-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The H2 receptor has been implicated in a number of disorders, including peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD), dyspepsia, and stress ulcer prophylaxis.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

Specifications

Accession Number	BC054510.2
Cell State	Dividing Cells
Description	GeneBLAzer™ H2-CRE-bla HEK 293T Cells, 2 x 106 Cells, ∽2,000,000 cells/vial at 2,000,000 cells/mL Quantity of Cells, 293T (HEK) Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage
For Use With (Application)	FRET
Includes	GeneBLAzer™ H2-CRE-bla HEK293T cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: GeneBLAzer™ H2-CRE-bla HEK293T cells, GeneBLAzer™ H2-CRE-bla HEK293T Assay Protocol, Certificate of Analysis
Product Line	GeneBLAzer™
Reporter Gene	BLA (Beta-Lactamase)
Target Entry	HRH2, H2
Cell Line	293T (HEK)
Druggable Target	GPCR

Assay Entry	Cell-based beta lactamase reporter gene
Content And Storage	LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol Includes: • GeneBLAzer™ H2-CRE-bla HEK293T cells • GeneBLAzer™ H2-CRE-bla HEK293T Assay Protocol • Certificate of Analysis The GeneBLAzer™ H2-CRE-bla HEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method	Fluorescence
Gene Symbol	HRH2
Population Status	Single Cell Clone Origin
Quantity	2 x 10⁶ Cells
Sample Type	293T (HEK)
Type	Cell Line
System Type	GeneBLAzer™

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Documents

Product Information

Manuals

User Guide: GeneBLAzer H2-CRE-bla HEK 293T Cell–Based Assay Version: 2.0 File size: 383.9 kB

GeneBLAzer® H2 CRE-bla HEK 293T Cell Line Validation Packet Version: version 1.1 File size: 91.1 kB

Certificates

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Lot Number

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Lot Number	Certificate Type	Date	Catalog Number
Lot Number36310	Certificate TypeCertificate of Analysis	Date16/04/2017	Catalog NumberK1707

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