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Fexaramine, Tocris Bioscience™

Product Code. 18075392
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Potent, selective farnesoid X receptor (FXR) agonist

Potent, selective farnesoid X receptor agonist (EC50 = 25 nM). Displays no activity at hRXRα, hPPARα, hPPARγ, hPPARδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ and hVDR receptors.

Chemical Identifiers

CAS 574013-66-4
Molecular Formula C32H36N2O3
Molecular Weight (g/mol) 496.651
InChI Key VLQTUNDJHLEFEQ-KGENOOAVSA-N
Synonym fexaramine, fex, d01myo, fexaramine hplc, e-3-3-cyclohexanecarbonyl-4-dimethylamino-biphenyl-4-ylmethyl-amino-phenyl-acrylic acid methyl ester, e-methyl 3-3-n-4'-dimethylamino-1,1'-biphenyl-4-yl methyl cyclohexanecarboxamido phenyl acrylate, 2-propenoic acid, 3-3-cyclohexylcarbonyl 4'-dimethylamino 1,1'-biphenyl-4-yl methyl amino phenyl-, methyl ester, 2-propenoic acid,3-3-cyclohexylcarbonyl 4'-dimethylamino 1,1'-biphenyl-4-yl methyl amino phenyl-,methyl ester, 3-4'-dimethylamino-4-biphenylylmethyl cyclohexylcarbonyl amino cinnamic acid methyl ester, 3-3-cyclohexylcarbonyl-4'-dimethylamino-1,1'-biphenyl-4-yl methyl amino phenyl-2-propenoic acid methyl ester
PubChem CID 5326713
ChEBI CHEBI:80003
IUPAC Name methyl (E)-3-[3-[cyclohexanecarbonyl-[[4-[4-(dimethylamino)phenyl]phenyl]methyl]amino]phenyl]prop-2-enoate
SMILES CN(C)C1=CC=C(C=C1)C2=CC=C(C=C2)CN(C3=CC=CC(=C3)C=CC(=O)OC)C(=O)C4CCCCC4

Specifications

Quantity 10 mg
Formula Weight 496.64
Percent Purity >97%
Chemical Name or Material Fexaramine
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