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Factor VII Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA5115207
323.34 EUR valid until 2025-03-29
Use promo code "24111" to get your promotional price.
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Description
Antibody detects endogenous levels of total Factor VII.
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
Specifications
Factor VII | |
Polyclonal | |
Unconjugated | |
F7 | |
AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA | |
Rabbit | |
Affinity chromatography | |
RUO | |
14068, 2155, 260320 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P08709, P70375, Q8K3U6 | |
F7 | |
A synthesized peptide derived from human F7(Accession P08709), corresponding to amino acid residues C187-L237. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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Product Title
Factor VII Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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