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Eact, Tocris Bioscience™

Product Code. 30001541
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Activator of Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A)

TMEM16A (ANO1) calcium-activated chloride channel (CaCC) activator (EC50 = 3 μM). Also transient receptor potential vanilloid 1 (TRPV1) channel activator (EC50 = 11.6 μM). Ca2+-independent. Displays no effect on CFTR Cl- or ENaC Na+ conductance. Stimulates submucosal gland secretion in human bronchi.

Chemical Identifiers

CAS 461000-66-8
Molecular Formula C22H24N2O5S
Molecular Weight (g/mol) 428.503
InChI Key ZUXNHFFVQWADJL-UHFFFAOYSA-N
Synonym eact, 3,4,5-trimethoxy-n-2-methoxyethyl-n-4-phenyl-1,3-thiazol-2-yl benzamide, eact hplc, 3,4,5-trimethoxy-n-2-methoxy-ethyl-n-4-phenyl-thiazol-2-yl-benzamide, 3,4,5-trimethoxy-n-2-methoxyethyl-n-4-phenyl-2-thiazolyl benzamide, 3,4,5-trimethoxy-n-2-methoxyethyl-n-4-phenylthiazol-2-yl benzamide, n-4-phenylthiazole-2-yl-n-2-methoxyethyl-3,4,5-trimethoxybenzamide
PubChem CID 3173542
IUPAC Name 3,4,5-trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
SMILES COCCN(C1=NC(=CS1)C2=CC=CC=C2)C(=O)C3=CC(=C(C(=C3)OC)OC)OC

Specifications

Quantity 10 mg
Formula Weight 428.5
Percent Purity >99%
Chemical Name or Material Eact
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