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  6. (+)-Dehydroisoandrosterone, 99%, Thermo Scientific Chemicals

(+)-Dehydroisoandrosterone, 99%, Thermo Scientific Chemicals

Product Code. 10488310
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Quantity:
2.5 g
10 g
50 g
Packaging:
Glass bottle
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This item is not returnable. View return policy

Description

(+)-Dehydroisoandrosterone, CAS # 53-43-0, also known as androstenolone, is an endogenous steroid hormone precursor. It is an intermediate in the conversion of cholesterol to androgens and estrogens.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• (+)-Dehydroisoandrosterone is an endogenous steroid hormone precursor that acts as an intermediate in the conversion of cholesterol to androgens and estrogens
Applications
• It is an endogenous and naturally occurring steroid hormone produced largely by the adrenal glands, but also by the testes and ovaries
• It has been described that (+)-Dehydroisoandrosterone could have a role in the immune and stress response
• (+)-Dehydroisoandrosterone can be converted to testosterone, androstenedione, estradiol, and estrone
• (+)-Dehydroisoandrosterone is derived from cholesterol through the action of two cytochrome P450 enzymes
• It can induce both direct and indirect in vivo biological effects, by modulating GABA- α receptor and N-Methyl-D-aspartic acid (NMDA) receptor complexes.
• It can also increase pancreatic β cell insulin secretion and anti-glucocorticoid activity
• It is useful to detect excess adrenal activity since it is produced nearly exclusively by the adrenal glands
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 53-43-0
Molecular Formula C19H28O2
Molecular Weight (g/mol) 288.42
MDL Number MFCD00003613
InChI Key FMGSKLZLMKYGDP-USOAJAOKSA-N
Synonym dehydroepiandrosterone, dhea, prasterone, dehydroisoandrosterone, androstenolone, trans-dehydroandrosterone, 3beta-hydroxyandrost-5-en-17-one, diandron, diandrone, psicosterone
PubChem CID 5881
ChEBI CHEBI:28689
IUPAC Name (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
SMILES CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)O)C

Specifications

CAS Min % 98.5
CAS Max % 100.0
Melting Point 146.0°C to 151.0°C
Color White
Loss on Drying 0.5% max. (105°C, 3 hrs)
Infrared Spectrum Authentic
Assay Percent Range 98.5% min. (HPLC)
Packaging Glass bottle
Quantity 10 g
Beilstein 08, IV, 994
Merck Index 15, 2875
Specific Rotation + 12.00
Solubility Information Solubility in water: practically insoluble. Other solubilities: soluble in benzene,alcohol and diethyl ether,sparingly soluble in chloroform and petrol. ether
Formula Weight 288.42
Percent Purity 99%
Physical Form Fine Crystalline Powder
Chemical Name or Material (+)-Dehydroisoandrosterone
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Safety and Handling

Product Identifier
  • (+)-Dehydroisoandrosterone

RUO – Research Use Only

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