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DCA, Tocris Bioscience™

Product Code. 18732694
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Quantity:
100 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor

Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of KV1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo.

Specifications

CAS 2156-56-1
Quantity 100 mg
Molecular Formula C2HCl2NaO2
MDL Number MFCD00070489
Synonym sodium dichloroacetate, sodium 2,2-dichloroacetate, dichloroacetic acid sodium salt, acetic acid, dichloro-, sodium salt, ceresine, dichloroacetate sodium, dichloroctan sodny czech, sodium dichloroacetate usan, ccris 7697, dichloroacetic acid, sodium salt
InChI Key LUPNKHXLFSSUGS-UHFFFAOYSA-M
SMILES [Na+].[O-]C(=O)C(Cl)Cl
IUPAC Name sodium 2,2-dichloroacetate
Molecular Weight (g/mol) 150.92
PubChem CID 517326
Formula Weight 150.92
Percent Purity >98%
Chemical Name or Material DCA
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