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Invitrogen™ D4 Dopamine Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA591860
Description
Positive Samples: Mouse liver; Cellular Location: Cell membrane, Multi-pass membrane protein Immunogen sequence: MGNRSTADAD GLLAGRGPAA GASAGASAGL AGQGAAALVG GVLLIGAVLA GNSLVCVSVA TERALQTPTN SFIVSLAAAD LLLALLVLPL FVYSEVQGGA.
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Specifications
| D4 Dopamine Receptor | |
| Polyclonal | |
| Unconjugated | |
| DRD4 | |
| AW125663; D(2C) dopamine receptor; D(4) dopamine receptor; D4DR; D4R; D4RA; Dopamine 4 receptor; Dopamine D4 receptor; dopamine receptor 4; dopamine receptor D4; DRD4; Drd-4; seven transmembrane helix receptor | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 13491 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 0.35 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P51436 | |
| DRD4 | |
| A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DRD4 (P21917). | |
| 100 μL | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
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