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  7. Cytochalasin B, Thermo Scientific Chemicals

Cytochalasin B, Thermo Scientific Chemicals

Product Code. 15456849
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Quantity:
5 mg
10 mg

Description

An actin-disrupting agent

Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

Solubility
Freely soluble in DMF, DMSO or ethanol at room temperature

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 14930-96-2
Molecular Formula C29H37NO5
Molecular Weight (g/mol) 479.62
MDL Number MFCD00077704
InChI Key GBOGMAARMMDZGR-UHFFFAOYNA-N
Synonym cytochalasin b, cytochalasin b from helminthosporium dematioideum
PubChem CID 44634701
IUPAC Name 16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H,8H,9H,10H,12aH,13H,14H,15H,15aH,16H,17H,18H-oxacyclotetradeca[3,2-e]isoindole-2,18-dione
SMILES CC1C2C(CC3=CC=CC=C3)NC(=O)C22OC(=O)C=CC(O)CCCC(C)CC=CC2C(O)C1=C

Specifications

Melting Point 218°C to 221°C
Color White
Odor Odorless
Quantity 5 mg
UN Number UN1544
Beilstein 1096207
Merck Index 14,2790
Solubility Information Freely soluble in DMF, DMSO or ethanol at room temperature
Formula Weight 479.61
Physical Form Powder
Chemical Name or Material Cytochalasin B
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Safety and Handling

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Product Identifier
  • Cytochalasin B
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 1
  • Acute toxicity Category 2
  • Reproductive toxicity Category 2
 Hazard Statement
  • H300-Fatal if swallowed.
  • H310-Fatal in contact with skin.
  • H330-Fatal if inhaled.
  • H361-Suspected of damaging fertility or the unborn child.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P310-Immediately call a POISON CENTER/doctor/.
 Supplemental information
  • MIXTURE LIST-Contains : Cytochalasin B

RUO – Research Use Only

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