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Tocris Bioscience™ CY 09

Inflammasomes Inhibitors

Brand: Tocris Bioscience™ 6436/10

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Product Code. 18783198

266.00€ / 10mg

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Description

CY 09 is a NLRP3 inhibitor (Kd = 500 nM); directly binds to ATP-binding motif of NLRP3 NACHT domain. Blocks NLRP3 inflammasome assembly and activation. Displays therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes. Exhibits no activity for hERG (10 μM).

Specifications

Chemical Name or Material	4-[[4-Oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]benzoic acid
Quantity	10 mg
Purity	98%

CAS	1073612-91-5
Molecular Formula	C₁₉H₁₂F₃NO₃S2

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Tocris Bioscience™ CY 09

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