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CPT 11, Tocris Bioscience™

Product Code. 18752534
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

DNA topoisomerase I inhibitor; antitumor

Inhibitor of DNA topoisomerase I that displays antitumor activity against a range of tumor types. Active metabolite available ( SN 38, Cat. No. 2684).

Chemical Identifiers

CAS 100286-90-6
Molecular Formula C33H39ClN4O6
Molecular Weight (g/mol) 623.15
MDL Number MFCD01862255
InChI Key GURKHSYORGJETM-WAQYZQTGSA-N
Synonym irinotecan hydrochloride, irinotecan hcl, topotecin, campto, cpt-11, cpt 11, camptothecin 11 hydrochloride, camptothecin 11, unii-06x131e4oe
PubChem CID 74990
ChEBI CHEBI:5971
IUPAC Name hydrogen (19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate chloride
SMILES [H+].[Cl-].CCC1=C2C=C(OC(=O)N3CCC(CC3)N3CCCCC3)C=CC2=NC2=C1CN1C2=CC2=C(COC(=O)[C@]2(O)CC)C1=O

Specifications

Quantity 10 mg
Formula Weight 623.14
Percent Purity >99%
Chemical Name or Material CPT 11
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