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CP 154526, Tocris Bioscience™

Product Code. 18074272
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective, non-peptide CRF1 antagonist

Selective, non-peptide CRF1 receptor antagonist (Ki values are 2.7 and > 10000 nM for CRF1 and CRF2 receptors respectively). Blocks CRF-induced adenylate cyclase activation (Ki = 3.7 nM) and attenuates activation of the HPA axis by CRF. Displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.

Chemical Identifiers

CAS 257639-98-8
Molecular Formula C23H33ClN4
Molecular Weight (g/mol) 400.995
InChI Key ZWDLBNCJWNENFF-UHFFFAOYSA-N
Synonym cp-154526 hydrochloride, cp 154526 hydrochloride, n-butyl-n-ethyl-2,5-dimethyl-7-2,4,6-trimethylphenyl-7h-pyrrolo 2,3-d pyrimidin-4-amine hydrochloride, cp-154526 hydrochloride hplc, n-butyl-n-ethyl-2,5-dimethyl-7-2,4,6-trimethylphenyl-7h-pyrrolo 2,3-d pyrimidin-4-amine monohydrochloride, n-butyl-n-ethyl-2,5-dimethyl-7-2,4,6-trimethylphenyl pyrrolo 2,3-d pyrimidin-4-amine hydrochloride
PubChem CID 11475094
IUPAC Name N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine;hydrochloride
SMILES CCCCN(CC)C1=NC(=NC2=C1C(=CN2C3=C(C=C(C=C3C)C)C)C)C.Cl

Specifications

Quantity 10 mg
Formula Weight 400.99
Percent Purity >99%
Chemical Name or Material CP 154526
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