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  6. Thermo Scientific Chemicals Calpeptin, ≥98%

Thermo Scientific Chemicals Calpeptin, ≥98%

Product Code. 15443249
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Inhibitor of the calcium-dependent protease calpain and cathepsin L

Calpeptin is used to to inhibit the activities of cathepsin L and calpain-1. Calpeptin blocked the expression of aspartyl protease cathepsin D, amyloid precursor protein, and calparin. It acts as an inhibitor of the Ca2+-dependent protease, calpain. Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Potent cathepsin L inhibitor. It is shown to preferentially inhibit a subset of protein-tyrosine phosphatases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 117591-20-5
Molecular Formula C20H30N2O4, C20H30N2O4
Synonym N-Benzyloxycarbonyl-L-leucyl-norleucinal; Z-Leu-norleucinal

Specifications

Quantity 10 mg
Description White
Content And Storage -30°C to -10°C
For Use With (Application) Inhibitor of the calcium-dependent protease calpain and cathepsin L
Formula Weight 362.50g/mol
Solubility Soluble in DMSO at 15mg/ml
Product Type Signal Transduction Reagent
Form Powder
InChI Key PGGUOGKHUUUWAF-ROUUACIJSA-N
SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O
IUPAC Name benzyl N-[(1S)-3-methyl-1-{[(2S)-1-oxohexan-2-yl]carbamoyl}butyl]carbamate
Molecular Weight (g/mol) 362.47
Assay ≥98%
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RUO – Research Use Only

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