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BMS 493, Tocris Bioscience™

Product Code. 18095692
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Quantity:
10 mg
50 mg
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Description

Pan-RAR inverse agonist

Pan-retinoic acid receptor (pan-RAR) inverse agonist. Enhances nuclear corepressor (NCoR) interaction with RARs. Binding induces analogous conformational changes in all RAR types (RARα, RARβ and RARγ).

Chemical Identifiers

CAS 215030-90-3
Molecular Formula C29H24O2
Molecular Weight (g/mol) 404.509
InChI Key YCADIXLLWMXYKW-CMDGGOBGSA-N
Synonym 4-1e-2-5,6-dihydro-5,5-dimethyl-8-2-phenylethynyl-2-naphthalenyl ethenyl benzoic acid, epothilone folate conjugate, d0n2gc, bms hplc, bms-748285 folate conjugate, bristol-myers squibb, 4-e-2-5,5-dimethyl-8-phenylethynyl-5,6-dihydro-2-napht, targeted epothilone-folate conjugate endocyte technology, cancer , bms, e-4-2-5,5-dimethyl-8-phenylethynyl-5,6-dihydronaphthalen-2-yl vinyl benzoic acid, 4-e-2-5,5-dimethyl-8-phenylethynyl-5,6-dihydronaphthalen-2-yl ethenyl benzoic acid, targeted epothilone-folate conjugate endocyte technology, cancer , bristol-myers squibb
PubChem CID 9909190
IUPAC Name 4-[(E)-2-[5,5-dimethyl-8-(2-phenylethynyl)-6H-naphthalen-2-yl]ethenyl]benzoic acid
SMILES CC1(CC=C(C2=C1C=CC(=C2)C=CC3=CC=C(C=C3)C(=O)O)C#CC4=CC=CC=C4)C

Specifications

Quantity 50 mg
Formula Weight 404.5
Percent Purity >98%
Chemical Name or Material BMS 493
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