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BD Pharmingen™ IHC Zinc Fixative

An alternative to formalin fixation of tissue for paraffin embedded sections

120.00€ - 380.00€

Specifications

Color Clear
Content And Storage Room temperature
Product Type Fixative
For Use With (Application) Immunohistochemical staining
Form Liquid
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Products 2
Product Code Brand Quantity Dilution Price Quantity & Availability  
Product Code Brand Quantity Dilution Price Quantity & Availability  
10400275
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BD
550523 		1000mL 1 X
120.00€
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15886838
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BD
552658 		500mL 10 X
380.00€
Each
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Description

Description

Ten percent neutral buffered formalin fixes tissue by cross-linking proteins, potentially causing a conformational change or “masking” of the antigenic epitope and leading to reduced or absent antibody reactivity. Different antigen retrieval techniques are used to unmask the epitope; however, many times it is not possible to retrieve the epitope and get optimal immunohistochemical staining. In these situations the use of IHC Zinc fixative, which is a milder fixative than formalin, is recommended.

  • Zinc-fixed paraffin embedded sections show very good immunostaining with many leukocytes markers and depict tissue morphology comparable to formalin-fixation
  • Use of antigen retrieval techniques on the zinc-fixed paraffin sections may further enhance the antibody reactivity in some cases

There are a few antigens that are not preserved by zinc-fixation. In these situations use of fresh frozen tissue for immunohistochemical staining is the only alternative.

Specifications

Specifications

Clear
Fixative
Liquid
Room temperature
Immunohistochemical staining
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BD Pharmingen™ IHC Zinc Fixative

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