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Tocris Bioscience™ AZD 5582 dihydrochloride
Dimeric Smac mimetic; potent IAP inhibitor
294.00€
Specifications
| Purity | >97% |
|---|---|
| Product Type | AZD 5582 dihydrochloride |
| Molecular Weight (g/mol) | 1088.21 |
| Inhibitors | AZD 5582 dihydrochloride |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18709017
|
Tocris Bioscience™
5141/10 |
10 mg |
294.00€
10mg |
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Description
Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice.Specifications
| >97% | |
| AZD 5582 dihydrochloride | |
| 1088.21 | |
| AZD 5582 dihydrochloride |
For Research Use Only