missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Azepanes
  7. AK 7, Tocris Bioscience™

AK 7, Tocris Bioscience™

Product Code. 30001574
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective SIRT2 inhibitor; brain penetrant

Selective SIRT2 inhibitor (IC50 = 15.5 μM); displays no effect on SIRT1 or SIRT3. Decreases neuronal cholesterol levels; improves motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Brain penetrant.

Chemical Identifiers

CAS 420831-40-9
Molecular Formula C19H21BrN2O3S
Molecular Weight (g/mol) 437.35
MDL Number MFCD03140195
InChI Key IYAYHZZWYNXHEQ-UHFFFAOYSA-N
Synonym ak-7, 3-azepan-1-ylsulfonyl-n-3-bromophenyl benzamide, ak 7, 3-azepane-1-sulfonyl-n-3-bromophenyl benzamide, 3-1-azepanylsulfonyl-n-3-bromophenyl benzamide, sirt2 inhibitor, ak-7, sirt2 inhibitor ii ak-7, benzamide, n-3-bromophenyl-3-hexahydro-1h-azepin-1-yl sulfonyl, ak hplc, n-3-bromophenyl-3-hexahydro-1h-azepin-1-yl sulfonyl benzamide
PubChem CID 1328033
IUPAC Name 3-(azepane-1-sulfonyl)-N-(3-bromophenyl)benzamide
SMILES BrC1=CC=CC(NC(=O)C2=CC(=CC=C2)S(=O)(=O)N2CCCCCC2)=C1

Specifications

Quantity 10 mg
Formula Weight 437.35
Percent Purity >98%
Chemical Name or Material AK 7
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.