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Tocris Bioscience™ Ac-FLTD-CMK

Potent and selective inhibitor of caspases 1, 5 and 4

Brand: Tocris Bioscience™ 7242/1

Product Code. 18035742

462.00€ / 1mg

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Description

Ac-FLTD-CMK is a potent and selective inhibitor of caspases 1, 5 and 4 (IC50 values = 46.7 nM, 0.33 μM, 1.49 μM, respectively), and inhibits murine caspase-11 at 10 μM. Ac-FLTD-CMK inhibits cleavage of gasdermin D by caspases, suppresses pyroptosis and reduces IL-1β release in macrophages.

Specifications

CAS	2376255-48-8
Target	Caspase Inhibitors
Purity	0.95

Quantity	1 mg
Molecular Formula	C₂₆H₃₇ClN₄O₈

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Tocris Bioscience™ Ac-FLTD-CMK

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