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Tocris Bioscience™ AA 147

ER proteostasis regulator

Brand: Tocris Bioscience™ 6759/25

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Product Code. 18737386

443.00€ / 25mg

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Description

AA 147 is an endoplasmic reticulum (ER) proteostasis regulator. Activates the ATF6 transcriptional program independently of ER stress and/or global UPR activation. Selectively reduces secretion of amyloidogenic transthyretin (TTR) from HepG2 cells. Reduces amyloidogenic immunoglobulin light chain (ALLC) secretion from ALMC-2 cells (EC50 = 1.1 μM).

Specifications

Chemical Name or Material	N-(2-Hydroxy-5-methylphenyl)benzenepropanamide
Quantity	25 mg
Formula Weight	255.31

CAS	393121-74-9
Molecular Formula	C₁₆H₁₇NO₂
Purity	98%

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Tocris Bioscience™ AA 147

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