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  7. A 887826, Tocris Bioscience™

A 887826, Tocris Bioscience™

Product Code. 18095802
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Quantity:
10 mg
50 mg
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Description

Potent voltage-dependent NaV1.8 channel blocker

Potent voltage-dependent NaV1.8 channel blocker (IC50 = 11 nM in recombinant human NaV1.8 channels). Reduces tactile allodynia in neuropathic rat models. 3- and 28-fold more potent at NaV1.8 channels compared to NaV1.2 and NaV1.7 channels respectively.

Chemical Identifiers

CAS 1266212-81-0
Molecular Formula C26H29ClN4O3
Molecular Weight (g/mol) 480.993
InChI Key JPJGFWKHSMUKFO-UHFFFAOYSA-N
Synonym 5-4-butoxy-3-chlorophenyl-n-2-morpholin-4-yl pyridin-3-yl methyl pyridine-3-carboxamide, a hplc, 5-4-butoxy-3-chlorophenyl-n-2-4-morpholinyl-3-pyridinyl methyl-3-pyridine carboxamide, 5-4-butoxy-3-chlorophenyl-n-2-4-morpholinyl-3-pyridinyl methyl-3-pyridinecarboxamide
PubChem CID 46919335
IUPAC Name 5-(4-butoxy-3-chlorophenyl)-N-[(2-morpholin-4-ylpyridin-3-yl)methyl]pyridine-3-carboxamide
SMILES CCCCOC1=C(C=C(C=C1)C2=CC(=CN=C2)C(=O)NCC3=C(N=CC=C3)N4CCOCC4)Cl

Specifications

Quantity 10 mg
Formula Weight 480.99
Percent Purity >97%
Chemical Name or Material A 887826
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