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A 419259 trihydrochloride, Tocris Bioscience™

Product Code. 18004892
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Quantity:
10 mg
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Description

Inhibitor of Src family kinases

Potent Hck inhibitor (IC50 = 0.43 nM). Also inhibits other Src family kinases (SFKs). Suppresses proliferation and induces apoptosis in CML cell lines including CD34+. Also inhibits acute myeloid leukemia (AML) stem cell proliferation in vitro and in vivo.

Specifications

CAS 1435934-25-0
Molecular Formula C29H37Cl3N6O
Quantity 10 mg
Synonym a 419259 trihydrochloride, a-419259 trihydrochloride, c29h34n6o.3clh, a-419259 trihydrochloride hplc, 5-4-phenoxyphenyl-7-1r,4r-4-4-methylpiperazin-1-yl cyclohexyl pyrrolo 2,3-d pyrimidin-4-amine trihydrochloride, 7-trans-4-4-methyl-1-piperazinyl cyclohexyl-5-4-phenoxyphenyl-7h-pyrrolo 2,3-d pyrimidin-4-amine trihydrochloride
InChI Key ALRMEQIQFCUAMR-UHFFFAOYSA-N
SMILES CN1CCN(CC1)C2CCC(CC2)N3C=C(C4=C3N=CN=C4N)C5=CC=C(C=C5)OC6=CC=CC=C6.Cl.Cl.Cl
IUPAC Name 7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine;trihydrochloride
Molecular Weight (g/mol) 592.006
PubChem CID 76848881
Formula Weight 592.01
Percent Purity >98%
Chemical Name or Material A 419259 trihydrochloride
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