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1-(Trimethylsilyl)imidazole, 97%, Thermo Scientific Chemicals

Product Code. 11498710
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1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.

Solubility
Miscible with most common organic solvents. It decomposes in water.

Notes
Moisture and light sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong acids.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 18156-74-6
Molecular Formula C6H12N2Si
Molecular Weight (g/mol) 140.26
MDL Number MFCD00005280
InChI Key YKFRUJSEPGHZFJ-UHFFFAOYSA-N
Synonym n-trimethylsilyl imidazole, 1-trimethylsilyl imidazole, 1-trimethylsilyl-1h-imidazole, tsim, 1h-imidazole, 1-trimethylsilyl, n-trimethylsilylimidazole, trimethylsilyl imidazole, 1-trimethylsilylimidazole, n-trimethylsilyl imidazol, imidazole, 1-trimethylsilyl
PubChem CID 28925
ChEBI CHEBI:85063
IUPAC Name imidazol-1-yl(trimethyl)silane
SMILES C[Si](C)(C)N1C=CN=C1

Specifications

Melting Point -42°C
Density 0.956
Boiling Point 212°C
Flash Point 18°C (64°F)
Odor Weak
Refractive Index 1.4765
Quantity 100 g
UN Number UN1993
Beilstein 606148
Sensitivity Moisture sensitive
Solubility Information Miscible with most common organic solvents. It decomposes in water.
Formula Weight 140.26
Percent Purity 97%
Chemical Name or Material 1-(Trimethylsilyl)imidazole
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RUO – Research Use Only

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