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1,1-Dimethylbiguanide Hydrochloride, MP Biomedicals™

Product Code. 11401211

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25 g

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Description

1,1-Dimethylbiguanide Hydrochloride, White Powder

It has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2.
It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
1,1-Dimethylbiguanide, Hydrochloride (Metformin) is a biguanide antihyperglycemic agent. 1,1-Dimethylbiguanide hydrochloride (metformin) is a strong base.
It forms well defined salts and possessing excellent coordination capacity with transition metals, forming highly colored bidentate chelate complexes.
Metformin (MET) exists in various forms: diprotonated (H2MET)2+ in strong acidic solution, monoprotonated (HMET)+ in weak acid, MET in neutral and deprotonated (MET)- in strong alkali solution. It is an oral antidiabetic drug.
Pharmacokinetics of metformin has been studied. Determination of metformin in human plasma has been described by simple HPLC-UV method.[5] Metformin is reported to increase plasma active glucagon-like peptide-1 (GLP-1) in humans

CAS	1115-70-4
Melting Point	214°C to 224°C
Color	White
Molecular Formula	C4H12ClN5
MDL Number	MFCD00012582
Quantity	25 g
Synonym	metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
Solubility Information	Soluble in water (100mg/mL - clear, colorless solution), 95% ethanol; insoluble in ether, acetone or chloroform.
InChI Key	OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES	[H+].[Cl-].CN(C)C(=N)N=C(N)N
IUPAC Name	3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride
Molecular Weight (g/mol)	165.63
PubChem CID	14219
Formula Weight	165.6
Physical Form	Powder
Chemical Name or Material	1, 1-Dimethylbiguanide Hydrochloride
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P264-Wash thoroughly after handling.
P280-Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P321-Specific treatment (see on this label).
P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

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