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1 – 15 of 37 results
1

Tocris Bioscience™ MZ 1

(+)-JQ1 based Degrader (PROTAC™) that selectively degrades BRD4

2

Tocris Bioscience™ Filipin III

Polyene antibiotic; inhibits formation of pathological isoform of prion protein

3

R&D Systems™ Human Serpin G1/C1 Inhibitor (Plasma) Protein

Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Inhibition Activity

5

Tocris Bioscience™ Ned K

NAADP signaling inhibitor

Content And Storage Store at -20°C
Product Type Inhibitor
Solubility Soluble to 50mM in DMSO
Color Cream
For Use With (Application) Prevents Ca2+ oscillations
Molecular Formula C31H31N5O3
Formula Weight 521.61g/mol
7

Tocris Bioscience™ NAV 2729

Selective ARF6 inhibitor

Content And Storage Store at 4°C
CAS 419547-11-8
Product Type Inhibitor
Solubility Soluble to 100mM in DMSO
Color Yellow
For Use With (Application) Blocks downstream signaling pathways
Molecular Formula C25H17ClN4O3
Formula Weight 456.88g/mol
8

Tocris Bioscience™ AZ 10397767

Potent CXCR2 antagonist

Content And Storage Store at -20°C
CAS 333742-63-5
Target Proteins Chemokine Receptor
Product Type Antagonist
For Use With (Application) Chemokine Receptor Antagonists
Molecular Formula C15H14ClFN4O2S2
Formula Weight 400.88g/mol
11

Tocris Bioscience™ B I09

IRE1 endonuclease inhibitor; cell permeable

Content And Storage Store at -20°C
CAS 1607803-67-7
Product Type Inhibitor
Solubility Soluble to 50mM in DMSO
Color Beige
For Use With (Application) Inhibits Rnase
Molecular Formula C16H17NO5
Formula Weight 303.31g/mol
12

Tocris Bioscience™ ML 315 hydrochloride

Low molecular weight, organic compound that may help regulate biological process.

Content And Storage Store at -20°C
CAS 1440251-53-5
Target Proteins Cdc2-like Kinase
Product Type Inhibitor
For Use With (Application) Cdc2-like Kinase Inhibitors
Molecular Formula C18H13Cl2N3O2.HCl
Formula Weight 410.68g/mol
13

Tocris Bioscience™ BOP

Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs

Promotions are available
Content And Storage Store at -20°C
Description N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt
CAS 1947348-42-6
Product Type Inhibitor
Solubility Soluble to 100mM in water and to 100mM in DMSO
Color White
For Use With (Application) Inhibits integrin
Molecular Formula C25H28N3O7SNa
Formula Weight 537.56
14

Tocris Bioscience™ FTY 720

Potent S1P receptor agonist; also immunosuppressant

Content And Storage Store at -20°C
CAS 162359-56-0
Target Proteins Sphingosine-1-phosphate Receptor
Product Type Agonist
Synonym Fingolimod, Gilenya
For Use With (Application) Sphingosine-1-phosphate Receptor Agonists
Molecular Formula C19H33NO2.HCl
Formula Weight 343.93g/mol
15

Tocris Bioscience™ Arformoterol Tartrate

Low molecular weight, organic compound that may help regulate biological process.

Content And Storage Store at 4°C
CAS 200815-49-2
Target Proteins Adrenergic beta-2
Product Type Long-acting Agonist (LABA)
For Use With (Application) Adrenergic beta-2 Receptor Agonists
Molecular Formula C19H24N2O4.C4H6O6
Formula Weight 494.49g/mol